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Domestic Birds as Carriers of Cryptococcus neoformans, the Main Cause of the Life Threatening Human Systemic Cryptococcosis

By walaa on June 15,2008

 

 M. Abdel-Razik 

ABSTRACT

      Samples of bird excreta including domestic pigeons were collected from farmer houses and aviaryshops in rural and urban areas of Ismailia. The collected samples were mycologically processed for theoccurrence of the pathogenic yeast, Cryptococcus neoformans. It was isolated mainly from pigeonexcreta and from only one sample of colored birds excreta collected from decorated colored bird'sshops. Pigeon excreta positive for Cryptococcus neoformans were suspended in sterilized phosphatebuffered saline then three different doses of the supernatant were interaperitoneally injected into groupsof experimental albino mice to assess its dissemination and the various pathological effects resultingfrom systemic infection. Mainly, pulmonary and occasional meningeal lesions were evident in theinfected mice.

Keywords: Cryptococcus neoformans, pigeon excreta, pulmonary, meningeal infection.



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